AI-ka Claude wuxuu ka helay DNA-baakariyada nidaam cusub oo noqon kara midka CRISPR
Shirkadda AI-ga ah ee Anthropic ayaa sheegtay in modelkeeda Claude uu 21 saacadood ku raadinayay baasaboorka DNA-baakariyada, kadibna uu ka helay nidaam enzyme cusub oo muujinaya nooc ka mid ah CRISPR.
Fahamka nidaamka cusub
Anthropic ayaa sheegtay in nidaamkaas uu muujiyo sifooyin la yaab leh oo la arkay kaliya ilbiriqsi kale oo 'programmable' ah, waxaana loo arkaa mid muujinaya 'pattern reminiscent of CRISPR'.
Shirkaddu waxay intaas ku dartay inay wali uusan go'aaminin shaqada nidaamkaas, balse ay ka xumahay inuu noqdo mid ka duwan CRISPR-ka hadda jira.
Hadallada hoggaamiyeyaasha
Dario Amodei, hoggaamiyaha Anthropic, wuxuu yiri: 'Waxaan u arkaa inay noqon karto nidaam cusub oo DNA-ga lagu beddelo', waxaana uu intaas ku daray inuu 'gacanta ku hayo' barnaamijyada AI-ga ah ee ku shaqeeya kaashanida dhaqaalaha.
Stanley Qi, macallin Stanford, wuxuu yiri: 'Waa mid aad u xiiso badan, waxaana ka muuqata awoodda uu leeyahay inuu ogaado noocyo cusub oo DNA-ga ah oo aan hore loo helin'.
Cabsida iyo xaqiiqada
Kevin Blake, macallin Washington University, wuxuu sheegay in 'CRISPR-ka hadda jira iyo kan cusub ay kala duwan yihiin, mana jiro wax muujinaya inuu noqon karo mid la isticmaali karo dhaqaalaha'.
Emmanuelle Charpentier iyo Jennifer Doudna, kuwa hore u helay Nobel-ka 2020-ka, waxay ahaayeen kuwa ugu horreeyay ee isticmaala CRISPR-ka, waxaana la sheegay in 2020-ka ay ku guuleysteen.
Anthropic announced that its AI model Claude autonomously identified a novel enzyme system in bacterial DNA after 21 hours of searching a large sequence database, displaying a pattern reminiscent of CRISPR.
AI-Powered Discovery in Anthropic's Biology Lab
Anthropic revealed on Wednesday that its Claude model had autonomously discovered a new enzyme system in bacterial DNA at the prompting of researchers at its San Francisco biology research lab. The system exhibited characteristics found in only a handful of other programmable structures and displayed a pattern reminiscent of CRISPR.
The tech giant stated it had not yet determined the function of the system. CEO Dario Amodei said his company suspects the molecular machine could represent a new gene editing mechanism, adding that AI is only at the very beginning of making discoveries that could lead to medical breakthroughs.
Mixed Reactions from the Scientific Community
Stanley Qi, an associate professor of bioengineering at Stanford University, described the reported discovery as incredibly exciting, noting that AI could greatly expand the ability to explore molecular systems more effectively and rapidly. He highlighted the system's ability to recognize an unusual biological pattern that was difficult to detect before.
However, Kevin Blake, a microbiologist at Washington University School of Medicine, expressed scepticism about the scientific significance of the announcement. He said there is nothing to indicate this is a rival to CRISPR-the-technology, or could be developed into any kind of therapeutic or practical application.
Context: CRISPR's Legacy and Real-World Impact
Emmanuelle Charpentier and Jennifer Doudna pioneered the use of the naturally occurring CRISPR system to edit DNA in living organisms, earning the pair the 2020 Nobel Prize in Chemistry. Their work has advanced the treatment of diseases including sickle cell disease and cancer.
Last year, the Children's Hospital of Philadelphia announced that doctors had treated a patient with a customised CRISPR gene-editing therapy for the first time. The hospital developed a bespoke therapy to successfully treat an infant born with carbamoyl phosphate synthetase 1 deficiency, a rare metabolic disease.
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